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The Silicone Hydrogels website is partially supported through an educational grant from CIBA VISION

 
Editorial | Previous Editorials
November 2001

 

SILICONE HYDROGELS IN PRACTICE
PART 1: Patient Selection and Fitting


Deborah Sweeney -
BOptom (UNSW) 1980 PhD (UNSW) 1992

Deborah Sweeney is Professor and Chief Executive Officer of the Vision Cooperative Research Centre.  Her major research area has been corneal physiology, and her work has been instrumental in developing an understanding of the physiology of the human cornea and the effects of contact lens wear on corneal function characteristics.  Associate Professor Sweeney is also active in national and international optometric and ophthalmic organizations, including Executive roles in the International Society for Contact Lens Research, The Keratoprosthesis (KPro) Study Group and the International Association of Contact Lens Educators.

 

Introduction
Patient Selection
Fitting
Wear Schedules
Conclusion
References

 

Introduction

Our patients have a strong desire to be free of the need for vision correction. They complain of not being able to see in the morning, or contact lens routines interfering with their lifestyles, and many have considered laser surgery to give them the 'continuous vision' they seek [1].

The new silicone hydrogel contact lenses offer continuous vision without surgery. Now that we have lens materials available that can overcome hypoxia and all its related problems, we need to consider how to integrate these products into our practices and offer this exciting development in vision correction to our patients.

Patient appreciation of these new contact lens options, and the additional challenges of CW practice can be a very positive addition to routine optometric practice. And of course contact lenses can be an important part of the financial success of a practice [2,3,4]. The introduction of silicone hydrogels is likely to increase the demand for contact lenses, and these satisfied patients can provide additional revenue through referrals and sales of accessories.

In Part I of this editorial we will cover patient selection and fitting with silicone hydrogels, and next month in Part II we will address patient management, aftercare, and education.


Patient selection 

Correct patient selection is important to achieving successful extended wear. The selection criteria for high Dk lens wear is very to similar to that for low Dk hydrogel lenses. A thorough ocular and general health history is the key to identifying the potential patient. It is also useful to remember that the silicone hydrogel lenses can be worn for 30 nights continuously, and or can be used as a daily wear lens, increasing the range of suitable patients.

Refractive error: Clearly the patient must fall within the spherical parameter range available in silicone hydrogel lenses. At present, high Dk silicone hydrogels are currently only available in the spherical form and therefore are not suitable for patients with astigmatism = 1D. Previously, fitting of high myopes and hypermetropes with lenses to be worn on an EW basis was strongly advised against because the lens thickness profiles further reduced the oxygen transmissibility of the already low Dk lenses. High Dk silicone hydrogels have overcome this limitation, and now offer the opportunity of CW to these patient groups.

General and ocular health: The physiological status and integrity of the cornea is a most important consideration in selecting a patient for CW. A detailed patient history and a biomicroscopic assessment of the anterior eye and tear layer should be done, to determine whether there are any contra-indications to contact lens wear. For example, patients who have compromised immunity, severe allergies or are using systemic medication should avoid extended wear altogether. There should be no irregular corneal distortion, and any degree of corneal staining or infiltration must be resolved before CW commences.

Unacceptable corneal staining prior to commencement of CW
Infiltrates [circled above] must have resolved before commencing CW
The quality of the tear layer will also be an important factor in the success of any contact lens wear, and the practitioner should avoid CW for patients with poor tear quality, excessive contamination or insufficient tears. Below is a checklist of pre-fit ocular health conditions which can be used as a guideline before prescribing CW.
Pre-fit checklist on ocular health [Brennan NA, Coles MLC - In: Sweeney 2000] [5]
Characteristic Requirement
Comfort Grade 3 (comfortable) or better
Subjective vision rating Grade 3 (good) or better
Visual acuity Within 1 line of best spectacle acuity
Hypoxic effects

No microcyst or vacuoles
No striae or signs of visible oedema

Limbal vascularisation <0.5 mm vessel penetration
Corneal staining None
Endothelial polymegethism Grade 1
Changes in corneal curvature No irregular corneal distortion or warpage
Infiltrates None
Bulbar and palpebral conjunctival redness Grade 1
Palpebral conjunctival papillae Grade 1
Conjunctival staining Grade 1
Note: Existing contact lens wearers may show some degree of microcysts, vacuoles or corneal distortion, and clinical judgement should be used to assess suitability for fitting. One fifth of asymptomatic patients may also exhibit corneal staining [6], however CW lenses should not be fitted until any significant corneal staining or infiltrates are resolved.
Patient history: Patient history is important in identifying potentially problematic patients. Patients that have had a prior history of inflammatory events or contact lens intolerance (contact lens papillary conjunctivitis) may be at greater risk of developing further inflammatory events.
Typical appearance of a patient experiencing CLARE (Contact Lens Acute Red Eye)
Typical signs of CLPC
(Contact Lens Papillary Conjunctivitis)

Inflammatory events are known to recur in extended wear [7,8] and patients should be aware of the risk of repeat events. Given both the modulus and surface characteristics of high Dk silicone lenses, patients with any signs and symptoms of CLPC with previous lens wear should not be considered as CW candidates. It is also important to beware of patients that are problematic with daily wear of contact lenses or that cannot maintain a 6-night extended wear schedule. Chronic low levels of discomfort [9,10,11] is one of the major reasons that patients discontinue from wearing soft contact lenses. However previous success or failure with CW is an uncertain indicator of success with the modality.

Motivational factors can also assist in the selection of the suitable patient. The magnitude of refractive error is the most apparent factor linked to motivation [12], however vocational, lifestyle, recreational, and self-image factors will also play a role.

Hygiene and compliance issues must always be addressed. While the convenience of CW is an important motivational factor, the desire for convenience per se is not necessarily sufficient for fitting CW, as the desire for convenience may be linked to a propensity for non-compliant behaviour. Non-compliance can be a major issue in the development of contact lens complications [13,14,15] therefore it is essential that patients are educated on the importance of lens hygiene and correct maintenance procedures. Patients that are non-compliant with lens maintenance solutions, hygiene and wear schedule are at increased risk of microbial contamination [13].

Fitting

It is important to ensure that patients have well fitted lenses to minimise the risk of mechanically-induced adverse responses and to provide optimum comfort. Trial lens fitting should always be done before the commencement of extended wear and, if there is any problem with fit, then an alternative design or product should be tried.

Assessment of lens fitting, following settling of the lens (10 minutes minimum), should involve evaluation of optimal centration, corneal coverage and lens movement. Ideally, high Dk silicone hydrogel lenses should be slightly loose (45-50% tightness) when assessed with a push-up test [16], with 0.2 to 0.3 mm movement and good limbal coverage in all gaze positions. Silicone hydrogels move more that most other spherical soft lenses.

The main aim is to maximise lens movement to achieve increased tear exchange. Lenses that are too loose can cause discomfort and lens awareness, and lenses that are too tight will prevent adequate tear exchange. This tear exchange is not for the purpose of oxygenation, but to encourage the removal of debris and bacteria from under the lens. It is generally considered good practice to fit CW lenses as mobile as possible, but there should be no compromise in comfort.

In a comparison of the percentage of unsuccessful fits in patients with high Dk silicone hydrogel lenses (n = 190) to those with conventional low Dk lenses (n = 115), we found that there was no difference in the percentage of patients who could not be fitted with lenses (4 and 5%, respectively) but that the cause of unsuccessful fits was different [5]. The primary reason for ill-fitting low Dk soft contact lenses was insufficient coverage of the limbus and decentration whereas lens 'fluting' was the primary cause of ill-fitting lenses with high Dk patients. Lens fluting is a buckling of the lens edge due to excessive edge lift, which occurs intermittently and can be detected by observing the lens edge move over the temporal limbal area near the lower lid.

Fluting at 5.30 o'clock as observed with white light
Instillation of fluorescein or flurexon may assist in the observation and will also indicate any bearing zones.

Fluting at 5 o'clock easily observed with flurexon using
cobalt blue light source and Wratten filter.

Lens fluting will not decrease with wear and will cause discomfort. Therefore if fluting or edge lift occurs, the trial lens should be considered unacceptable. There is no period of adaptation with silicone hydrogel lenses, therefore comfort should be optimised at the first fitting.
Wear Schedules

We recommend that if a patient is new to lens wear, then they should undergo a short period (minimum of 1 week) of adaptation to high Dk lenses on a daily wear schedule. The patient should be completely comfortable with lens handling and care procedures before they move into CW. If there are no problems, the patient should then commence extended wear. The patient should wear the lenses for one night and then come in for a check; and proceed to 6 nights wear then come in for a second check; before starting 30-night continuous wear. This not only gives the patient time to become accustomed to lens wear, but also allows the practitioner to assess the response of the eye to the silicone hydrogel material. Experienced lens wearers with no history of ocular complications can commence extended wear with high Dk lenses immediately.

Although high Dk silicone hydrogel lenses are designed for up to 30 nights of extended wear, patients and practitioners should be encouraged to have a flexible attitude to lens wear schedules. Lenses can be worn continuously for any length of time up to 30 nights. Patients should be encouraged to remove their lenses as often as is thought necessary, particularly if they are unwell. Lenses that are removed temporarily should be rinsed or cleaned before reinsertion and lenses that are removed overnight or for any significant period of time should be disinfected before they are reinserted. Practitioners should ensure that patients do not use their lens hygiene and maintenance solutions beyond their expiry date.

Aftercare regimes will be discussed in more detail in Part 2 of this editorial, however it is important that patients new to high Dk should be seen after the first night of wear, then after the first week, first month, at 3 months, and every 3 months thereafter.

Conclusion
Patient selection which takes into account health, personality and circumstances; and lens fitting to ensure maximum comfort and minimum lens effects on the eye, will help to ensure the future success of continuous wear. Awareness of these factors will make it easy for practitioners to add the benefits of CW to their practice, and to provide their patients with the 'continuous' vision they seek.
References

[1] Vision Cooperative Research Centre (VisionCRC) studies 2000
[2] Ziegler D (1997): Maintaining profitability in these competitive times. Cont Lens Spectrum 12: 29-32
[3] Barr J (1998): The 1997 annual report on contact lenses. Cont Lens Spectrum 13: 23-33
[4] Marrioneaux S, Gwin N (1998): The golden opportunity in contact lenses. Cont Lens Spectrum 13: 27-32
[5] Sweeney DF (editor): Silicone Hydrogels: The rebirth of continuous wear contact lenses. Butterworth-Heinemann, Oxford, 2000
[6] Norn MS (1972): Vital staining of cornea and conjunctiva. Cont Lens J 3: 19-22
[7] Bates AK, Morris RJ, Stapleton F, Minassian DC, Dart JKG (1989): Sterile infiltrates in contact lens wearers. Eye 3: 803-810
[8] Sweeney DF, Grant T, Chong MS, Fleming C, Wong R, Holden BA (1993): Recurrence and acute inflammatory conditions with hydrogel extended wear. Invest Ophthalmol Vis Sci 34: S1008
[9] Cox N (1985): Contact lens drop outs. J Br Contact Lens Assoc. 8: 6-10
[10] Weed KH, Fonn D, Potvin R (1993): Discontinuation from contact lens wear. Optom Vis Sci 70: S140
[11] Fonn D, Pritchard N, Brazeau D, Michaud L (1995): Discontinuation of contact lens wear: The numbers, reasons and patient profiles. Invest Ophthalmol Vis Sci 36: S312
[12] Efron N, Brennan N, Sek B (1988): Wearing patterns with HEMA contact lenses. Int Cont Lens Clin. 15: 344-350
[13] Bowden FW, Cohen EJ, Arentsen JJ, Laidson PR (1989): Patterns of lens care practices and lens product contamination in contact lens microbial keratitis. CLAO J 15: 49-54
[14] Ky W, Scherick K, Stenson S (1998): Clinical survey of lens care in contact lens patients. CLAO J 24: 216-219
[15] Gower LA, Stein JM, Turner FD (1994): Compliance: A comparison of three lens care systems. Optom Vis Sci. 71: 629-634
[16] Young G, Holden BA, Cooke G (1993): Influence of soft contact lens design on clinical performance. Optom Vis Sci 70: 394-403

 

 
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